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Antidepressants and antipsychotics could serve as alternatives to opioids, study finds

Medications that target depression, anxiety and poor sleep could help treat pain without opioids’ addictive properties

A range of other medications could serve as alternatives to powerful opioids for pain relief in emergency departments, according to a new study.

The review paper examined non-opioid medications available in the emergency department at San Francisco general hospital and examined existing medical literature to figure out which ones might provide pain relief.

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Jun 14, 2026 Opioids Opioids crisis US news

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